ECLIPSE Lab led the 2025 ISEE conference with multiple symposia and presentations on systems biology and environmental health.

Co-Chairs: Tanya Alderete & Donghai Liang
Presenter: Holzhausen

Systems Biology Meets Environmental Health: Omics Approaches to Maternal and Child Health among Vulnerable Populations

This symposium showcased how cutting-edge omics approaches—including genomics, epigenomics, metabolomics, and microbiomics—help unravel the molecular mechanisms linking environmental exposures to maternal and child health. Presentations highlighted studies on pollutants, PFAS, pesticides, and endocrine-disrupting chemicals, with a focus on vulnerable populations. By integrating systems biology with environmental health, the session identified biomarkers, clarified pathways, and informed strategies to improve maternal and child health outcomes.

Co-Chairs: Tanya Alderete & Lida Chatzi
Presenter: Alderete

Unraveling the Links Between PFAS Exposure and Cancer Risk: Advances in Research and Mechanistic Insights

This symposium examined the emerging evidence linking PFAS exposure to cancer risk and treatment outcomes, drawing on epidemiology, toxicology, and systems biology. Presentations highlighted findings on colorectal, liver, and reproductive cancers, integrating insights from human cohorts, in vitro models, and metabolomics approaches. Together, these studies identified key knowledge gaps, elucidated mechanistic pathways, and underscored the importance of interdisciplinary research to guide prevention and policy.