What is this?
This study tracks two birth cohorts of mother–infant pairs to age 6, examining how early nutrition, toxins, and social factors affect adiposity, eating, brain development, cognition, and chronic disease risk. Assessments include body composition, cognitive tests, MRI, and exposure evaluations. The goal is to understand the long-term effects of early nutrition—especially human milk oligosaccharides—environmental toxins, and social determinants on physical, metabolic, and brain development in Latino children, identifying pathways influencing chronic disease risk.
Publications
PMID: 36609302; PMCID: PMC9817265
The impact of social determinants of health on obesity and diabetes disparities among Latino communities in Southern California.
PMID: 38299034 PMCID: PMC10828959
The potential role of early life feeding patterns in shaping the infant fecal metabolome: implications for neurodevelopmental outcomes.
PMID: 38931150 PMCID: PMC11206877
Maternal Diet Associated with Oligosaccharide Abundances in Human Milk from Latina Mothers.
PMID: 37717629 PMCID: PMC10808822
Associations between Dietary Sugar and Fiber with Infant Gut Microbiome Colonization at 6 Mo of Age.
PMID: 40923624
Social and Environmental Correlates of Childhood Obesity Among Southern California Communities. Epub ahead of print.
PMID: 36972018 PMCID: PMC10202769
Rapid Decline in β-Cell Function and Increasing Adiposity Are Associated With Conversion to Type 2 Diabetes in At-Risk Latino Youth.
PMID: 39059708 PMCID: PMC11393400
Consumption of different combinations of human milk oligosaccharides in the first 6 mo of infancy is positively associated with early cognition at 2 y of age in a longitudinal cohort of Latino children.
PMID: 37905810 PMCID: PMC10734492
Characterizing alterations in the gut microbiota following postpartum weight change.
PMID: 38600046
Pre-pregnancy maternal obesity and infant neurodevelopmental outcomes in Latino infants.
PMID: 39454357 PMCID: PMC11578286
Ambient air pollution exposure is associated with liver fat and stiffness in Latino youth with a more pronounced effect in those with PNPLA3 genotype and more advanced liver disease.